49ers Draft C.J. West from Indiana at No. 113

The San Francisco 49ers selected Indiana defensive tackle C.J. West with the 113th overall pick in the fourth round of the 2025 NFL Draft, marking the highest Indiana defensive lineman draft pick since 1991. West, who transferred from Kent State and played one season for the Hoosiers, was a key presence on their defensive line and earned All-Big Ten honorable mention. Scouts and analysts praise his athleticism, quick first step, high motor, and ability to disrupt the run game, though they note concerns about his shorter stature, limited pass-rush production, and lack of length. West had a standout NFL Combine with a 4.95-second 40-yard dash, a 33-inch vertical jump, and a 9.15 Relative Athletic Score, further boosting his draft stock. The 49ers are expected to use West as part of a defensive line rotation, valuing his run defense and potential in a one-gap attacking scheme, despite needing technical refinement to impact passing downs. The pick underscores San Francisco's focus on bolstering its defensive front in this draft.